Here, we evaluate the performance of 64-channel graphene sensor arrays in terms of homogeneity, sensitivity and stability using a wireless, quasi-commercial headstage and demonstrate the biocompatibility of epicortical graphene chronic implants. However, in order to provide reliable tools for neuroscience and biomedical engineering applications, the maturity of this technology must be thoroughly studied. Their functional properties, together with their flexibility as well as their expected stability and biocompatibility have raised them as a promising building block for large-scale sensing neural interfaces. active sensors have demonstrated promising capabilities for the detection of electrophysiological signals in the brain. Lluís Companys 23, 08010, Barcelona, Spain. 9 Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra, 08193, Barcelona, Spain. 8 Bernstein Center for Computational Neuroscience Munich, Faculty of Medicine, Ludwig-Maximilians Universität München, Planegg-Martinsried, Germany.1 Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra, 08193, Barcelona, Spain.
7 Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK.6 Nanomedicine Lab, National Graphene Institute and Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK.5 Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain.4 Instituto de Microelectrónica de Barcelona, IMB-CNM (CSIC), Esfera UAB, Bellaterra, Spain.3 Multi Channel Systems (MCS) GmbH, Reutlingen, Germany.2 Bernstein Center for Computational Neuroscience Munich, Faculty of Medicine, Ludwig-Maximilians Universität München, Planegg-Martinsried, Germany.1 Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra, 08193, Barcelona, Spain.
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